Onion has Antidiabetic Property -How much quantity you should consume?

Onion has Antidiabetic Property -How much quantity you should consume?

Onion has Antidiabetic effects on the body as we all know Diabetes is most likely to become the seventh-largest killer in the world by the year 2030. Studies have shown that there are multiple flavonoids (a class of antioxidants)  and sulphur compound present in onion that help keep the blood glucose in control.

Antidiabetic effect of onion.

Onions were shown to have significant oral hypoglycemic  action, comparable to that of the prescription oral hypoglycemic agents tolbutamide and phenformin. The substance responsible for the hypoglycemic effect in onions is believed to be allyl propyl disulphide, although other constituents such as quercetin and anthocyanidin may play a significant role as well.

Experiment for antidiabetic Effects

Experimental and clinical evidence suggested that allyl propyl disulphide lowered glucose by competing with insulin (also a disulfide) for degradation sites, thereby increasing the half-life of insulin. Other mechanisms, such as increased hepatic metabolism of glucose or increased insulin secretion, have been proposed.

Measured Therapeutical dosage for antidiabetic effects

In one assessment of the hypoglycemic activity of onion consumption in type 1 and type 2 diabetic patients, ingestion of 100 g of onion caused a considerable reduction in fasting blood glucose levels by about 89 mg/dL in relation to insulin (145 mg/dL) in type 1 diabetic patients, and it reduced fasting blood glucose levels by 40 mg/dL compared with glibenclamide (81 mg/dL) in type 2 diabetic patients, 4 hours later.

The same dose of onion produced a significant reduction in induced hyperglycemia (glucose tolerance test) by about 120 mg/dL compared with water (77 mg/dL) and insulin (153 mg/dL) in type 1 diabetic patients and considerably reduced the glucose tolerance test by 159 mg/dL in relation to water (55 mg/dL) and glibenclamide (114 mg/dL) in type 2 diabetic patients, after 4 hours.

DOSAGE. Onions can be eaten liberally as part of a nutritious diet. Therapeutic dosages in the various forms are typically equal to 50 to 150 g/day of raw onion

Reference:

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978938/
2. https://pubmed.ncbi.nlm.nih.gov/21079693/
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892491/

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